Composition:

Ingredients:

Each 100ml has:

Florfenicol                                                  200 gm

N-methyl 2 Pyrrolidine                               550 gm

Ethanol                                                       As required.

What type of antibiotic is Florfenicol?

Chloramphenicol is a highly effective and well-tolerated broadspectrum antibiotic. Thiamphenicol is less effective but safer than chloramphenicol. Florfenicol, a thiamphenicol derivative, is significantly more active in vitro than chloramphenicol against many pathogenic strains of bacteria

Mechanism of Action

Florfenicol is a bacteriostatic antibiotic that inhibits protein synthesis by binding to ribosomal subunits of susceptible bacteria, leading to the inhibition of peptidyl transferase and thereby preventing the transfer of amino acids to growing peptide chains and subsequent protein formation

Why Florfenicol? 

  1. Florfenicol is highly lipophilic, which provides high enough concentrations to treat intracellular pathogens and cross some anatomic barriers

This means that after administration with Flustop 20 sol readily enters tissues,  which results in wide distribution of antibiotic

With the tissue distribution and speed of action, we can be confident that Flustop 20 sol® (florfenicol) is an excellent first choice
antibiotic for treating Respiratory & Gastrointestinal diseases

  1. It’s a new molecule for our country. So the pathogen resistant to antibiotic for treating Respiratory & digestive diseases are sensitive to Florfenicol

Why Florfenicol?

  • Broad-spectrum antimicrobial effect
  • The drug is effective in small concentrations
  • Therapeutic blood concentration is maintained within 24 hours after oral administration.
  • Florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with chloramphenicol  
  • Also has activity against some chloramphenicol-resistant strains of bacteria. 

Contraindications

It is not allowed to use in combination with thiamphenicol and chloramphenicol, penicillin antibiotics, cephalosporins and fluroquinolones.

Indications

  • Treatment of Respiratory Diseases such as Infectious coryza(Haemophilus paragallinarum), Respiratory colibacillosis(E. coli), Ornithobacteriosis(Ornithobacterium rhinotracheale), Bordetellosis(Bordetella avium), Mycoplasmosis & secondary infection of viral diseases
  • Salmonellosis
  • Streptococcosis 
  • Fowl Cholera(Pasteurella spp.)
  • some other microorganisms sensitive to Florfenicol.

Field of Administration

 

Salmonellosis, Colibacillosis, Fowl Cholera

Dosage and Administration

Poultry: 

Dissolve 0.5ml per Liter of drinking water & administer for 3-5 days

Or put 0.1ml per kg of Body Weight (Florfenicol 20mg) into drinking water & administer for 3-5 days

Supply: 100 ml & 500ml